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Nanomolar to Picomolar Converter
↔ Convert pM to nM instead

Common Conversions

nM pM
0.001 1
0.01 10
0.1 100
0.5 500
1 1000
5 5000
10 10000
100 100000
1000 1000000
10000 10000000
100000 100000000
1000000 1000000000

Why this conversion matters in chemistry

Lead-optimization SAR work is a typical place to need it. A 5 nM IC50 for an early kinase-inhibitor candidate is 5000 pM — three decades above the 10 pM lower-bound a fragment-screening campaign might define. The conversion lets a medicinal-chemistry team set the next-round optimization target on the same numeric scale as the ceiling derived from structural biology. That 1000 pM per nM is the nano and pico prefix step, no more. Mostly it's a unit-system step between the two scales of binding affinity in a typical hit and lead campaign.

Formula

pM = nM × 1000

Worked Examples

1 nM = 1000 pM

The conversion anchor — the nano to pico prefix step.

0.1 nM = 100 pM

A sub-nanomolar concentration — the high-affinity end of routine binders.

0.001 nM = 1 pM

1 pM — about the ceiling of routine antibody-antigen affinity.

10 nM = 10000 pM

About a typical mid-stage drug-candidate IC50 value.

Frequently Asked Questions

How do I convert nM to pM?
Multiply by 1000. So 0.5 nM becomes 500 pM. The relationship is exact through the nano and pico prefix step.
Why convert to picomolar?
Comparing results across assays running on different sensitivity scales, or expressing sub-nanomolar concentrations in a more readable form. The pM scale keeps high-affinity values in single- or low double-digit numbers where nM would push them below 0.01.
What's the molarity-prefix relationship?
1 nM = 1000 pM = 10⁻⁹ M. 1 pM = 10⁻¹² M. Each prefix step is 1000-fold, geometric and exact through the SI prefix system.