Skip to main content

Barium Sulfate

BaSO4 salt

Properties

StateSolid (fine white powder)
ColorWhite
SolubilityExtremely insoluble in water (0.0024 g/L at 25°C)
Melting Point1580°C
Boiling Point1600°C (decomposes)

About Barium Sulfate

Barium sulfate is the textbook insoluble salt — its Ksp of 1.1 × 10⁻¹⁰ is roughly four orders of magnitude smaller than the next least-soluble alkaline-earth sulfate (CaSO4 at Ksp = 4.9 × 10⁻⁵), and the disparity is what makes BaSO4 so useful in three otherwise unrelated applications. In medicine, the same insolubility that makes barium ions invisible to the GI tract makes barium sulfate the safe radiopaque contrast agent for upper-GI series and barium-enema imaging — patients drink or are given a thick suspension of BaSO4, and the heavy barium absorbs X-rays strongly enough to outline the gastrointestinal mucosa with millimeter resolution. Despite Ba²⁺ being a Group 1 muscle-channel toxin, essentially zero ions enter solution as the suspension passes through, so BaSO4 administration is safe at gram-level doses. In oilfield drilling, the same density (4.5 g/cm³) that makes BaSO4 X-ray opaque makes it the standard weighting agent for drilling muds — adding ground barite to the mud raises the column density to 1.4–2.4 g/cm³, which keeps high-pressure formation fluids contained until the wellhead seal is established. Around 80% of all mined barite goes into drilling mud. The third use, as the white pigment 'blanc fixe' in paints and paper coatings, takes advantage of BaSO4's high refractive index, complete chemical inertness, and resistance to weathering. In analytical chemistry, BaSO4 precipitation remains a standard gravimetric assay for sulfate determination at percent levels, even after instrumental ion chromatography has displaced it for trace work.

Where you'll encounter it

If you've ever undergone an upper-GI series or barium enema, the chalky white slurry you swallowed was a barium sulfate suspension stabilized with thickeners and sweeteners, dosed at 100–200 g of BaSO4 per study. The contrast image you saw on the radiology film was X-ray attenuation by Ba's K-edge at 37 keV. In the oil and gas industry, barite mining is a multibillion-dollar global market specifically because drilling muds need the density and chemical inertness — substitutes like hematite or galena exist but barite remains the standard. In a paint store, the white-pigment can labeled 'blanc fixe' or 'permanent white' contains BaSO4 as the active filler; it's used in artist's gesso primers and in some industrial paints because it doesn't yellow with age the way some other white pigments do.

Common Uses

  • Radiopaque contrast suspension for upper-GI and barium-enema imaging
  • Weighting agent in oilfield drilling mud (~80% of mined barite use)
  • Blanc-fixe white pigment for paints, gesso, and paper coatings
  • Inert filler in plastics and rubber for density and X-ray shielding
  • Gravimetric standard for percent-level sulfate-anion determination

Safety Information

Practically inert because of insolubility — the medical-grade material is administered to patients orally and rectally with negligible systemic absorption, and the industrial-grade barite is non-hazardous in routine handling. The exception is dust inhalation in mining and grinding operations, where chronic exposure to fine BaSO4 dust (without other toxic contaminants) produces baritosis, a benign pneumoconiosis with characteristic chest-radiograph findings but no functional impairment. Standard industrial dust controls and N95 respiratory protection are sufficient.

This safety summary is for educational reference only and may not be complete. It is not a substitute for Safety Data Sheets (SDS), medical advice, or professional chemical safety guidance. Always consult appropriate SDS and qualified professionals before handling chemicals.

Constituent Elements

Frequently Asked Questions

What is the molar mass of barium sulfate?
233.39 g/mol. Sum 137.33 for the barium, 32.06 for the sulfur, and 4(15.999) for the four oxygens, giving 233.39. The number is what shows up in the gravimetric analysis calculation: dry the BaSO4 precipitate, weigh it, divide the mass by 233.39, and the resulting moles equal the moles of sulfate that were in the original sample.
Why is barium sulfate safe to swallow despite barium being toxic?
Solubility-driven dose isolation. Free Ba²⁺ ions are toxic via potassium-channel blockade, but BaSO4's Ksp of 1.1 × 10⁻¹⁰ means that even in stomach acid the saturation concentration of dissolved Ba²⁺ is below 1 µM — far too low to produce the cardiac or muscular effects that gram-scale soluble-barium ingestions cause. The clinical preparation is essentially a colloidal suspension in water with thickeners, and it passes through the GI tract as a contrast medium without any pharmacokinetic absorption. The single counterexample is when the GI tract has a perforation that lets BaSO4 enter the peritoneum, where prolonged contact with serum can release enough Ba²⁺ to produce systemic toxicity — which is why iodinated contrast agents are preferred when perforation is suspected.
What is gravimetric sulfate analysis?
Add excess BaCl2 solution to the unknown sulfate sample in slightly acidic conditions, allow the BaSO4 precipitate to digest at near-boiling for an hour (which gives larger, more easily filterable crystals), filter through ashless paper, ignite the paper to drive off carbon, and weigh the resulting BaSO4 ash. The mass divided by 233.39 g/mol gives moles of sulfate originally present. The technique is laborious compared to ion chromatography but remains a primary standard method for sulfate at the percent level — most regulatory agencies still accept it as the reference method when ion chromatography results are disputed.