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Potassium Ferrocyanide

K4Fe(CN)6 salt

Properties

StateSolid (lemon-yellow crystals; trihydrate most common)
ColorLemon yellow
SolubilitySoluble in water (289 g/L at 20°C); insoluble in ethanol
Melting PointDecomposes at ~70°C (trihydrate loses water); anhydrous decomposes ~300°C
Boiling PointDecomposes before boiling

About Potassium Ferrocyanide

Potassium ferrocyanide, K4[Fe(CN)6], is the lemon-yellow Fe(II) sibling of red ferricyanide. The yellow color and diamagnetism both come from a low-spin d6 iron center sealed inside an octahedral cage of six cyanide ligands, with a formation constant around 10^35. That binding strength is why a salt containing six CN groups per formula unit ended up approved as food additive E536 — the European Food Safety Authority and FDA both treat it as safe because the cyanide simply does not dissociate at gastric pH. You'll see it on table salt ingredient lists in Europe at up to 20 mg/kg as an anti-caking agent, and winemakers use the bluefining (Blauschönung) process to drop excess copper and iron out of white wines as Prussian blue, which is then filtered out before bottling. In analytical chemistry, ferrocyanide is the classic spot-test reagent for Fe3+ — the resulting Fe4[Fe(CN)6]3 (Prussian blue) is so intense that low-ppm iron contamination in a clear solution turns the whole flask blue. In electrochemistry, the [Fe(CN)6]4-/3- couple at +0.358 V vs SHE is the standard one-electron reversible system everyone benchmarks new electrodes against.

Where you'll encounter it

If you've ever salted a steak with a European brand of table salt, sipped a German Riesling, or run a cyclic voltammogram in undergraduate physical chemistry, ferrocyanide has touched your day. In a winery lab, the bluefining titration uses a precisely calculated dose of K4[Fe(CN)6] based on prior ICP-OES analysis of the wine's iron and copper content — overshoot and you leave residual ferrocyanide; undershoot and the wine still hazes. In an electrochemistry lab, a freshly prepared 5 mM K4[Fe(CN)6] / 1 M KNO3 solution is what you scan to confirm a glassy carbon electrode is properly polished — anything wider than ~70 mV peak separation means the surface is fouled and needs another alumina pass.

Common Uses

  • Anti-caking additive E536 in European table salt at up to 20 mg/kg
  • Bluefining of white wine to remove copper and iron as Prussian blue precipitate
  • Spot test reagent for Fe3+ in qualitative inorganic analysis
  • Reference redox couple for cyclic voltammetry of new electrode surfaces
  • Component of cyanotype solution B in alternative-process photography
  • Case-hardening of steel in traditional Bower-Barff cyaniding heat treatment
  • Mordant in cotton dyeing for Prussian blue and saxon blue shades

Safety Information

GHS: not classified as hazardous at normal handling concentrations. Oral LD50 in rats is around 6400 mg/kg, and permitted dietary intake as a food additive is capped orders of magnitude below that. The cyanide is locked inside the coordination sphere with a formation constant near 10^35, which is why E536 cleared food-additive review. Never heat the dry salt with concentrated H2SO4 or HCl — that decomposes the complex and releases HCN, whose exposure limit is a ceiling rather than a time-weighted average. Avoid prolonged intense UV on solutions, which slowly photodecomposes to ferricyanide. Dispose through cyanide-compatible waste streams even though free CN- isn't released under normal use.

This safety summary is for educational reference only and may not be complete. It is not a substitute for Safety Data Sheets (SDS), medical advice, or professional chemical safety guidance. Always consult appropriate SDS and qualified professionals before handling chemicals. We deliberately do not publish occupational exposure limits or other regulatory thresholds: those values are revised over time and differ between jurisdictions, so the only correct source is the current SDS and the regulations that apply where you work.

Constituent Elements

Frequently Asked Questions

What is the molar mass of potassium ferrocyanide?
Anhydrous K4[Fe(CN)6] is 368.346 g/mol — four potassium (156.392) plus iron (55.845) plus six carbon (72.066) plus six nitrogen (84.042). The bottle on most lab shelves is the trihydrate K4[Fe(CN)6]·3H2O at 422.388 g/mol, so always check the label before weighing for a standard. Forgetting the waters of hydration is one of the most common errors in undergraduate inorganic prep.
How is potassium ferrocyanide safe if it contains cyanide?
The six cyanide ligands are octahedrally coordinated to Fe(II) with a formation constant near 10^35, which means the equilibrium concentration of free CN- in a neutral solution is essentially nothing. Stomach acid alone doesn't dislodge them. EFSA reviewed the data and set an ADI of 0.03 mg/kg body weight, and it appears in salt at concentrations no more than 20 mg/kg. The hazard appears only when you heat with strong acid, expose to intense UV, or burn the dry salt — all of which break the Fe-CN bonds.
What is the difference between ferricyanide and ferrocyanide?
Ferricyanide is K3[Fe(CN)6], iron in the +3 state, paramagnetic, bright red. Ferrocyanide is K4[Fe(CN)6], iron in the +2 state, diamagnetic, lemon yellow. The extra potassium in ferrocyanide balances the lower iron charge. They're a one-electron redox couple at +0.358 V vs SHE, so the same iron center cycles between yellow and red as it loses or gains an electron — that's why the system is so popular for teaching reversible electrochemistry.