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Uranium Hexafluoride

UF6 inorganic

Properties

StateSolid sublimating to gas at 56.5 °C (1 atm); triple point 64.0 °C at 151.7 kPa
ColorColorless
SolubilityReacts violently with water; soluble in liquid fluorocarbons and some organic solvents
Melting Point64.05 °C (at 151.7 kPa; sublimes at 1 atm)
Boiling Point56.5 °C (sublimation, 1 atm)

About Uranium Hexafluoride

Uranium hexafluoride is the only uranium compound volatile enough to handle as a gas at near-ambient temperatures, and that single property is the entire foundation of the commercial nuclear fuel cycle. The molecule is a perfect octahedron — six W-F... pardon, six U-F bonds of 1.99 Angstrom radiating from the central U(VI) — held together by strong covalent W=F sigma bonds with no Jahn-Teller distortion because U(VI) is d^0 f^0. The triple point sits at 64.05 °C and 151.7 kPa, just above atmospheric, so at 1 atm the solid sublimes directly to gas at 56.5 °C without passing through a liquid phase. This solid-to-gas transition with no intermediate liquid is the operational basis of every gas-centrifuge enrichment cascade in operation, from URENCO Almelo to Eurodif's successor Orano in Pierrelatte. Inside a Zippe-type centrifuge spinning at 60,000 to 90,000 RPM, the 0.85% mass difference between 235UF6 (349.03 g/mol) and 238UF6 (352.04 g/mol) is enough to push the lighter isotopologue toward the rotor axis and the heavier toward the wall — feed in 0.72% U-235 natural uranium, cascade thousands of centrifuges in series and parallel, and you can produce 5% LEU for power reactors or above 90% HEU for weapons. The fluorine in UF6 has only one stable isotope (19F), which is essential — any natural variation in F isotope distribution would smear out the U isotope signal.

Where you'll encounter it

If you have ever watched centrifuge cascade footage from URENCO or seen the famous declassified photos of the K-25 gaseous diffusion plant at Oak Ridge (a single U-shaped building covering 44 acres, the largest building in the world when completed in 1945), the working fluid in every pipe and seal was UF6. UF6 is shipped between conversion plants, enrichment plants, and fuel fabrication plants in Type 30B and Type 48Y steel cylinders that look like small submarines — heated to about 100 °C to vaporize the contents for transfer, then cooled and sealed for road or rail transport. The notorious incident at Sequoyah Fuels in Gore, Oklahoma in 1986 saw a single overfilled cylinder rupture during heating, releasing about 14 tonnes of UF6 that hydrolyzed in the air to a yellow cloud of UO2F2 and HF — one worker killed, dozens injured, and the plant never reopened. The subfab piping in any UF6 facility runs heat-traced and double-walled, with continuous HF leak detection at floor level because UF6 is heavier than air and HF will pool wherever the gas leaks.

Common Uses

  • Working gas for uranium isotope enrichment in gas-centrifuge cascades worldwide
  • Historical working gas for gaseous-diffusion enrichment at Oak Ridge K-25 and Paducah
  • Feedstock to fuel fabrication plants where it is converted to UO2 powder for pellet pressing
  • Intermediate in the back-end fuel cycle for re-enrichment of reprocessed uranium streams
  • Reference material in actinide chemistry for studies of high-oxidation-state fluorides
  • Calibration gas for mass spectrometers and centrifuge process diagnostics in enrichment plants
  • Working material in laser-isotope separation research (SILEX, AVLIS) for advanced enrichment routes
  • Test material for international safeguards verification of enrichment facility throughput and assay

Safety Information

EXTREMELY HAZARDOUS. GHS classification: Acute Toxicity Category 2 (oral, dermal, inhalation), Skin Corrosion Category 1A, Carcinogen Category 1B, Reproductive Toxicity Category 1B, Specific Target Organ Toxicity Repeated Exposure Category 2 (kidney), and Radioactive. The chemical toxicity from kidney-targeting U(VI) plus the HF generated by hydrolysis dominates over the radiological hazard at natural and low enrichments. The Sequoyah Fuels accident in 1986 demonstrated the worst-case scenario: a ruptured cylinder released 14 tonnes of UF6 that hydrolyzed to HF and UO2F2 fumes, killing one worker and injuring dozens. NRC handles regulation under 10 CFR 40 (source material) and 10 CFR 70 (special nuclear material above 1% enrichment), with criticality safety controls at all enriched-material facilities. Transport in Type 30B and 48Y cylinders under DOT class 7 radioactive plus class 8 corrosive. Decommissioning requires N2 purge of all wetted surfaces and neutralization of UF6 condensate to UO2 plus CaF2.

This safety summary is for educational reference only and may not be complete. It is not a substitute for Safety Data Sheets (SDS), medical advice, or professional chemical safety guidance. Always consult appropriate SDS and qualified professionals before handling chemicals.

Constituent Elements

Frequently Asked Questions

What is the molar mass of uranium hexafluoride?
UF6 has a molar mass of 352.02 g/mol using natural-isotopic U (238.029) + 6 F (113.988). The two key isotopologues are 235UF6 at 349.03 g/mol and 238UF6 at 352.04 g/mol — a 0.85% difference. This is the entire physical basis of centrifuge enrichment: spin a UF6 gas mixture fast enough and the heavier 238UF6 migrates radially outward, leaving the cascade product enriched in 235UF6. Doing the same separation with metallic uranium would require an isotope-mass difference at the level of 1.3% — not enough payoff.
Why is UF6 used for uranium enrichment instead of other compounds?
Three properties uniquely combine. First, volatility: UF6 sublimes at 56.5 °C, so the entire enrichment process can run as a gas phase at temperatures compatible with stainless steel and aluminum equipment. Second, fluorine has only one natural isotope (19F), so the molecular weight difference between isotopologues is entirely due to the U isotope difference — no fluorine isotope smearing. Third, UF6 forms with all the major U isotopes without significant chemical fractionation. UCl6 would also be volatile but Cl has two isotopes (35 and 37); uranium nitrates and oxides aren't volatile enough.
How is UF6 produced from uranium ore?
Mined uranium ore is leached with H2SO4 or alkaline carbonate, processed through ion exchange or solvent extraction, and precipitated as yellowcake (U3O8 or sodium diuranate). At a conversion plant the yellowcake is reduced with H2 to UO2, reacted with anhydrous HF at 500 °C to give UF4 ("green salt"), and finally fluorinated with elemental F2 in a fluidized-bed reactor at 500 °C: UF4 + F2 -> UF6. The product is condensed into Type 48Y cylinders and shipped to enrichment plants. Major conversion facilities operate at Metropolis Illinois (Honeywell, currently idled), Pierrelatte France (Orano), and Port Hope Canada (Cameco).